I didn't have specific registry key in the mentioned path, but this solution gave me an idea and i fixed the same issue like this:
open -> regedit
navigate -> Computer\HKEY_USERS\<user-id>\SOFTWARE\Microsoft\Windows NT\CurrentVersion\AppCompatFlags\Layers
add string registry key:
key -> C:\Games\L2-eGlobal\System\l2.bin
value -> ~ DPIUNAWARE
